moorepic_redshirt(1).jpg - 37738 Bytes Richard C. Moore
Assistant Professor
Ph.D. (1999) Pennsylvania State University
Office: 394 Pearson Hall
Office Hours: 10-12 M/W

Tel: (513) 529-4278
Fax: (513) 529-4243
Email: moorerc@muohio.edu


Plant evolutionary biology, evolutionary genetics and genomics, duplicate gene evolution, evolution of sexual reproduction systems, evolution of plant development (evo-devo).



Research Interests:
 

Morphological diversity, both within and between species, is the product of structural and functional changes in genes and genomes and the effect of such changes on developmental pathways. Understanding this relationship between genes, ontogeny, and the origins and diversification of species falls within the realm of evolutionary developmental biology.

As an evolutionary developmental biologist, I combine the fields of genomics, systematics, developmental genetics, and molecular evolutionary biology to discern the molecular mechanisms underlying the origin and evolution of morphological diversity. I am particularly interested in understanding the evolutionary and functional consequences of changes in plant genomes that have given rise to plant morphological and species diversity. In order to address this problem, it is necessary to understand how evolution acts upon plant genes and genomes, and the functional consequences of such evolutionary change.

I have focused my research efforts on microevolutionary processes that shape plant genomes in functionally relevant ways: 1) the evolution of sex chromosomes and sexual dimorphism and 2) the evolution of duplicate genes. Both of these processes exemplify how structural changes in the plant genome can lead to major innovations in plant development. By studying these processes on both genomic and functional levels, I hope to bridge the gap between genomics and morphological diversity.




Selected Publications:


Moore, R.C. and Stevens, M.H.H. (2008). Local patterns of nucleotide polymorphism are highly variable in the selfing species Arabidopsis thaliana. Journal of Molecular Evolution, in press.

Bergero, R., Charlesworth, D., Filatov, D.A. and Moore, R.C. (2008). Defining regions and rearrangements of the Silene latifolia Y chromosome. Genetics, in press.

Yu, Q., Hou, S., Feltus, A., Jones, M.R. Murray, J.E., Veatch, O., Lemke, C., Saw, J.H., Moore, R.C., Timmapuram, J., Liu, L., Moore, P.H., Alam, M., Jiang, J., Paterson, A.H., Ming, R. (2008). Low X/Y divergence in four pairs of papaya sex linked genes. Plant Journal 53: 124-132.

Cheng, X.-W., Wan X.-F., Xue, J., and Moore, R.C. (2007). Ascovirus and its evolution. Virologica Sinica, 22: 19.

Moore, R.C. and Purugganan, M.D. (2005). Evolutionary dynamics of plant duplicate genes. Curr. Opinion Plant Biol. 8:122-128.

Shimizu, K., Cork, J. M., Caicedo, A. L., Mays, C., Moore, R.C., Olsen, K. M., Ruzsa, S., Coop, G., Bustamante, C. D., Awadalla, P., and Purugganan, M.D. (2005). Darwinian selection on a selfing locus.
Science
306: 2081-2084.

Moore, R.C. and Purugganan, M.D. (2005). Evolutionary dynamics of plant duplicate genes. Curr. Opinion Plant Biol. 8:122-128.

Shimizu, K., Cork, J. M., Caicedo, A. L., Mays, C., Moore, R.C., Olsen, K. M., Ruzsa, S., Coop, G., Bustamante, C. D., Awadalla, P., and Purugganan, M.D. (2005). Darwinian selection on a selfing locus. Science 306: 2081-2084.

Moore, R.C., Grant, S.R., and Purugganan, M.D. (2005). Molecular population genetics of redundant floral developmental genes in Arabidopsis thaliana. Molecular Biology and Evolution 22:91-103.

Friedman, W.E.*, Moore, R.C. *, and Purugganan, M.D. (2004). The evolution of plant development. Amer. J. Botany 91:1726-1741. [*Joint first authorship].

Moore, R.C. (2004). Autosomes behaving badly. Heredity 93:126-127

Moore, R.C. and Purugganan, M.D. (2003). The early stages of duplicate gene evolution. Proc. Natl. Acad. Sci. USA. 100: 15682-15687.

Lengerova, M., Moore, R.C., Grant, S.R., Vyskot, B. (2003). The sex chromosomes of Silene latifolia revisited and revised. Genetics 165: 935-938.

Moore, R.C., Kozyreva, O., Lebel-Hardenack, S., Siroky, J., Hobza, R., Vyskot, B., Grant, S.R. (2003). Genetic and functional analysis of DD44, a sex-linked gene from the dioecious plant Silene latifolia provides clues to early events in sex chromosome evolution. Genetics 163:321-334.

Moore, R.C. and Cyr, R.J. (2000). The association between elongation factor-1a and microtubules in vivo is domain dependent and conditional. Cell Motility and the Cytoskeleton 45: 279-292.

Moore, R.C., Durso, N.A., and Cyr, R.J. (1998). Elongation factor-1a stabilizes microtubules in a calcium/calmodulin-dependent manner. Cell Motility and the Cytoskeleton 41: 168-180.

Moore, R.C., Zhang, M., Cassimeris, L., and Cyr, R.J. (1997). In vitro assembled plant microtubules exhibit a high state of dynamic instability. Cell Motility and the Cytoskeleton 38: 278-286.



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