Qingshun Quinn Li
, Associate Professor
http://www.polyA.org
Ph.D.
(1995) University of Kentucky
Areas of Expertise
Plant functional genomics, RNA biology,
molecular biology, biochemistry, and biotechnology.
Research Interests
Research in Dr. Li's lab focuses on the elucidation of plant mRNA polyadenylation mechanisms at the genetic, biochemical, and molecular levels. Funded by US National Science Foundation's Arabidopsis 2010 Project, and US National Institute of Health, we are using functional genomic tools to study the functions of a set of genes encoding plant polyadenylation factors. We are particularly interested in the regulatory role of mRNA polyadenylation in gene expression during plant development and stress responses.
Selected Publications
Denghui Xing, Hongwei Zhao, Ruqiang Xu and Q. Quinn Li. 2008. Arabidopsis PCFS4, a homologue of yeast polyadenylation factor Pcf11p, regulates FCA alternative processing and promotes flowering time. Plant Journal, in press.
Yingjia Shen, Guoli Ji, Brian J. Haas, Xiaohui Wu, Jianti Zheng, Greg J. Reese, and Q. Quinn Li. 2008. Genome level analysis of rice mRNA 3'-end processing signals and alternative polyadenylation. Nucleic Acids Research, in press
(doi:10.1093/nar/gkn158).
Chun Liang, Yuansheng Liu, Lin Liu, Adam C. Davis, Yingjia Shen, and Q. Quinn Li. 2008. ESTs with cDNA termini - previously overlooked resources for gene annotation and transcriptome exploration in Chlamydomonas reinhardtii. Genetics, 179:83-93.
Yingjia Shen, Yuansheng Liu, Lin Liu, Chun Liang, and Q. Quinn Li. 2008. Unique features of nuclear mRNA poly(A) signals and alternative polyadenylation in Chlamydomonas reinhardtii. Genetics, 179:167-176.
Arthur G. Hunt, Ruqiang Xu, Balasubrahmanyam Addepalli, Suryadevara Rao, Kevin P. Forbes, Lisa R. Meeks, Denghui Xing, Min Mo, Hongwei Zhao, Amrita Bandyopadhyay , Lavanya Dampanaboina, Amanda Marion, Carol Von Lanken, and Q. Quinn Li. 2008. Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. BMC Genomics, 9:220.
Ruqiang Xu and Q. Quinn Li. 2008. Streamline cloning of genes into binary vectors in Agrobacterium via the Gateway TOPO vector system. Plant Methods, 4:4.