Advanced Courses in Microbiology
MPT 201 General Microbiology I (4)
Consideration of fundamental aspects of structure, metabolism, genetics, and behavior of bacteria, archaea, viruses, and fungi. Laboratory stresses basic techniques and procedures common to all phases of science at professional level. Corequisite: CHM 231 or 241. 3 Lec. 1 Lab. CAS-D/LAB.
MBI 202 General Microbiology II (4)
Consideration of viruses, bacteria, archaea, fungi, and their evolution and microbiological subdisciplines of microbial ecology, applied microbiology, epidemiology, and immunology. Laboratory stresses techniques relevant to each course subject area. Prerequisite: MBI 201. Corequisite: CHM 242, 332, or permission of the instructor. 3 Lec. 1 Lab.
MBI 275 Principles of Environmental Science (3)
Introduction to the principles and methodologies of environmental science. Topics include contamination of earth systems and pollution mitigation; use, abuse and conservation of natural resources; land use, conservation and preservation, planning and management and the value of biodiversity and wilderness. Emphasis is on the multidisciplinary nature of environmental problems and their solutions. Does not count as credit toward an A.B. in microbiology. Prerequisites: At least one course from each of the following three categories is either pre- or co-requisite: 1) BOT/MBI/ ZOO 115 or BOT 191 or ZOO 113; 2) CHM 111 or CHM 142/5; and 3) GLG 111/115 or 121/115 or 141/115 or GEO 121.
MBI 277/377/477 Independent Study (1-4; maximum 8)
Research experience in the laboratory of a professor. Special attention given to the scientific method, literature searches, experimental design, and laboratory instrumentation and techniques. Prerequisite: MBI 201. (MPC 477C is a Miami Plan Capstone with concurrent enrollment in MBI 490C.)
340 Summer Internship (1-12) Laboratory research experience. Prerequisite: permission of instructor.
MPT 361 Epidemiology (3)
Consideration of the epidemic nature, etiology, and characteristics of infections and organic diseases, and methods used to analyze their control within the framework of environmental and population variables. Prerequisite: two hours of microbiology.
MPT 365 Molecular and Cell Biology (3)
Cellular and molecular mechanisms utilized by bacteria, bacterial viruses, eukaryotes and animal viruses in converting genetic information into functional macromolecules, transporting them, using them to receive signals that induce cellular effects, and controlling the cell cycle. Prerequisites: MBI 116, 201, or equivalent.
MBI 402/502 Geomicrobiology (3)
Focuses on mutual interactions between microbial and geological processes. Topics include: role of microorganisms on mineral weathering rates, microbial mediated ore deposit formation, microbe enhanced oil recovery, life in extreme environments, search for bio-signatures in geological records and meteorites and implications for life on Mars, microbial ecology in ocean floor hydrothermal vents. Prerequisite: Any 100-level, 3 credit hour GLG course; CHM 137 or 141, 144; or permission of instructor. Cross-listed with GLG.
MBI 405/505 Pathogenic Microbiology (4)
Pathogenic bacteria, their identification, and mechanisms by which they cause disease. Prerequisite: MBI 202. 3 Lec. 1 Lab.
MBI 414/514 Immunology Principles (3)
Lectures covering molecules, cells, tissues, and organs of the immune system. Primary emphasis on the mechanisms involved in immune responses. Prerequisite: MBI 202 (or permission of instructor) and CHM 242 or 332; recommended: MBI 365, ZOO 203, or ZOO 443.
MBI 415/515 Immunology Principles and Practice (4)
Covers the same content as MBI 414/514, but adds laboratory exercises and demonstrations illustrating a variety of immunologic phenomena, techniques, and applications. Credit not given for both MBI 414/514 and MBI 415/515. Prerequisite: MBI 202 (or permission of instructor) and CHM 242 or 332; recommended: MBI 365, ZOO 203, or ZOO 443. 3 Lec. 1 Lab.
MBI 424/524 Biological Instrumentation (4)
Theory and application of modern biological instrumentation and techniques such as spectrophotometers, pH meters, thermocyclers, and DNA sequencers. Basic and advanced skills including use, maintenance, and calibration of biological instruments. Prerequisites: BOT/MBI/ ZOO 115/116 or BOT 191 or MBI 201 or MBI 202 or ZOO 113/115 or ZOO 114/116 or equivalent, CHM 141/142 or equivalent, or permission of instructor. Cross-listed with BOT 424/524 and ZOO 424/524.
MBI 425/525 Microbial Physiology (4)
Biochemical activities of microorganisms as revealed by their cellular physiology. Prerequisite: MBI 202 and CHM 242 or 332. 3 Lec. 1 Lab.
MBI 435/535 Medical Mycology (3)
Characteristics of fungi associated with disease. Includes discussion of epidemiology, pathology, and diagnosis of mycotic diseases. Laboratory focuses on identification and biochemical activities of pathogenic fungi. Prerequisite: MBI 405/505 or BOT 421/521 or permission of instructor. 2 Lec. 1 Lab.
MBI 440 Research Problems (2; maximum 4)
Library research. Open to senior majors. Prerequisite: 20 hours of microbiology and permission of instructor. (MPC 440C is a Miami Plan Capstone with concurrent enrollment in MBI 490C)
445/545 Microbial Genetics (3)
Genetic changes that occur in bacteria and bacterial viruses and resulting changes in their biochemical and physiological activities. Prerequisite: MBI 425.
MBI 464/564 Human Viruses (3)
Study of the physical and chemical characteristics of viruses, virus replication mechanisms, disease causation and host response, and tumor induction. Prerequisite: MBI 202, or equivalent.
MBI 465/565 Microbial and Molecular Genetics Laboratory (2)
Laboratory methodology associated with experimental aspects of microbial genetics and recombinant DNA technique. Prerequisite: BOT 342 or ZOO 342, or MBI 445/545 or permission of instructor.
MBI 466/566 Bioinformatics Computing Skills (3)
Programming in Perl and MatLab. Use of BLAST, BioPerl, BioPHP, and MatLab Bioinformatics Toolbox. Emphasis placed on biological database design, implementation, management, and analysis. Prerequisite(s): Programming course and BOT 116, or BOT 342, or permission of instructor. Cross-listed with CSA/BOT/ ZOO 466/566.
MBI 475/575 Microbial Ecology: Exploration of the Diverse Roles of Microorganisms in Earth's Ecology (3)
Integrative examination of the evolution of life, distribution, and abundance of microorganisms, and biogeochemical cycles leading to the discovery of principles used for societal applications such as water quality management and bioremediation. Prerequisite: MBI 202 and CHM 242 or permission of instructor.
MBI 480 Departmental Honors (1-3; maximum 6)
Departmental honors may be taken for a minimum of one semester hour and a maximum of six semester hours in two semesters of student's senior year. (MPC 480C is a Miami Plan Capstone in conjunction with MBI 490C)
MBI 485/585 Bioinformatics Principles (3)
Concepts and basic computational techniques for mainstream bioinformatics problems. Emphasis placed on transforming biological problems into computable ones and seeking solutions. Cross-listed with BOT 485/585 and ZOO 485/585. Prerequisite: BOT/MBI/ ZOO 116 or MBI 201 or BOT/ ZOO 342 or CHM 332 or CHM 433 or permission of instructor.
MPC 487, 488, 489 Clinical Laboratory Science Practicum (8, 12, 12)
Off-campus, structured sequence of laboratory and lecture rotations through clinical chemistry, hematology, immunohematology, immunology, microbiology, molecular, and other emerging diagnostics laboratories. Structured lecture criteria accompany the corresponding laboratory rotations.
MBI 490 Undergraduate Seminar (1; maximum 4)
Discussion by undergraduate majors and staff of current topics in selected areas. Prerequisite: 20 hours of microbiology. (MPC 490C is a Miami Plan Capstone in conjunction with MBI 440C or MBI 477C or MBI 480C)
MBI 495/595 Bacterial Cellular and Developmental Biology (3)
Focuses on the biology of bacteria at the cellular level, including regulation of cell shape, cell division, motility, development and differentiation, and interactions with other cells, including life in a biofilm and in association with symbionts. Prerequisite(s): MBI 202.


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