111
Microorganisms and Human Disease

Course Outline - Fall 2009

Principles of Disease, Microorganisms as Parasitic Agents, and Epidemiology

August 25
Introduction and Overview (Text, p. 1-3, 5-17)
Infectious Disease Principles (Text, p. 6-7, 16-17, 379-405)
August 27
Description of Microorganisms: Bacteria (Text, p. 86-106, 192-197, 199-202) and Viruses (Text, p. 149, 166, 172-174), Eukaryotic Cells (Text, p. 117-129), Fungi (Text, p. 130-135), Protozoa (Text, p. 136-142, 181), Helminths (Text, p. 143-145)
September 1
Infectious Strategies of Microorganisms: Virulence Factors (Text, p. 141t, 383-392; Articles: "Study Immuminates How The Plague Bacteria Causes Disease" plus "Scientists Reveal How H5N1 Kills")
Epidemiology Principles (Text, p. 405-413; Article: "Salmonella Outbreak" plus "Eat That Tomato!" plus "Peanut Butter Link to Salmonella Outbreak")

Impact of Infectious Diseases on Development of Human Societies

September 3
Antiquity to Middle Ages: Malaria (Text, p. 627-632), African Sleeping Sickness (Text, p. 599-601), Schistosomiasis (Text, p. 725-726), Leprosy (Text, p. 358; Article: "Leprosy Was Spread by Colonialism, Slave Trade"), Plague (Text, p. 314, 615-617, 677; Article: "Bubonic Plague Traced to Ancient Egypt")
Middle Ages to Dawn of Microbiology as a Science: Overview (Text, p. 345), Plague (Text, p. 314, 615-617, 677), Smallpox (Text, p. 465, 549-551; Article: "Smallpox and Other Deadly Eurasian Germs")
September 8
Middle Ages to Dawn of Microbiology as a Science: Overview (Text, p. 345; Article: "Guns, Germs and Steel"), Syphilis (Text, p. 748-752), Cholera (Text, p. 702-704; Article: "How Epidemics Helped Shape the Modern Metropolis"), Tuberculosis (Text, p. 343, 354)
Era of Public Health and Discovery of Antibiotics: Overview (Text, p. 15-16, 349), Syphilis (Text, p. 748-752), Typhoid Fever (Text, p. 397, 697-698), Tuberculosis (Text, p. 666-671), Influenza (Text, p. 662-666; Video: "1918 Flu")
September10
Last 50 Years: AIDS (Text, p. 634-642, 733-734, 742), Avian Flu (Video: "Pandemic Flu") , Dengue Fever (Text, p. 622-623), Ebola Fever (Text, p. 623-624; Article: "Where Does Ebola Hide between Epidemics?"), Hantavirus Respiratory Syndrome (Text, p. 675), Legionnaire’s Disease (Text, p. 674), Lyme Disease (Text, p. 618-621), Mad Cow Disease (Text, p. 173-174, 588-590), SARS (Text, p. 149, 166, 675-677), West Nile Fever (Text, p. 585-586)

Human Defenses against Parasitism

September 15
Innate Host Defenses: Resistance (Text, p. 414-441)
September 17
Innate Host Defenses: Resistance (Text, p. 414-441)
Adaptive Host Defenses: Immunity (Text, p. 442-477)
September 22
Adaptive Host Defenses: Immunity (Text, p. 442-477)
September 24
Coping Strategies: Vaccines (Text, p. 464-473; Articles: "Vexing Vaccines" plus "No Link Between Measles Vaccine and Autism"), Disinfection (Text, p. 327-337, 794-798), Antimicrobial Chemotherapeutic Agents (CTAs) (Text, p. 246-249, 343-370)
Review, Synthesis and Integration of Concepts
September 29
Examination 1

Diseases Transmitted by Skin Infection

October 1
Background (Text, p. 535-538), Acne (Text, p. 538; Article: "Understanding Acne"), Impetigo (Text, p. 540-543), Furuncles (Text, p. 538, 544), Necrotizing Fasciitis (Text, p. 539), Candidiasis (Text, p. 135, 353, Wikipedia)
October 6
Tineas (Text, p. 558-561), Sporotrichosis (Wikipedia), Warts (Text, p. 555-557), Cutaneous Herpes (Wikipedia), Gangrene (Text, p. 545-546), Tetanus (Text, p. 596-597)
October 8
Anthrax (Text, p. 558, 632-633), Leprosy (Text, p. 358; Article: "Leprosy is not dead"), Ebola Fever (Text, p. 623-624), Rabies (Text, p. 590-592), Plague (Text, p. 615-617, 677), Lyme Disease (Text, p. 618-621), Rocky Mountain Spotted Fever (Text, p. 626-632)
October 13
Encephalitis (Text, p. 585-586, 626-627), Dengue Fever (Text, p. 622-623), Yellow Fever (Text, p. 623), Malaria (Text, p. 627-632; Article: "The Story of Malaria and other Deadly Tropical Germs"), African Sleeping Sickness (Text, p. 599-601), Schistosomiasis (Text, p. 725-726)

Diseases Transmitted by Respiratory Infection

October 15
Background (Text, p. 650-651), Colds (Text, p. 651-652, 661), Streptococcal Pharyngitis (Text, p. 555, 654-657), Otitis Media (Text, p. 653-654), Meningitis (Text, p. 574-578)
October 20
Rubella (Text, p. 553-554), Rubeola (Text, p. 535, 551-553, 555; Articles: "MMR doctor Andrew Wakefield fixed data on autism" plus "Most US Measles Cases Reported since 1996"), Varicella (Text, p. 546-549)
October 22
Variola (Smallpox) (Text, p. 465, 549-551), Infectious Mononucleosis (Text, p. 621-622), Diphtheria (Text, p. 657-659), Pertussis (Text, p. 649, 661)
October 27
Influenza (Text, p. 662-666; Articles: "Southern Hemisphere's swine flu experience holds hints of what may be ahead" plus "Health Expert Says Swine Flu Not Likely to Mirror 1918 Pandemic"), Pneumonia (Text, p. 671-675), Legionaire's Disease (Text, p. 676), Hantavirus Respiratory Syndrome (Text, p. 675)
October 29
Tuberculosis (Text, p. 666-671; Article: "Drug Resistant TB May Be Treatable"), Histoplasmosis (Text, p. 677-679)
Review, Synthesis and Integration of Concepts
November 3
Examination 2

Diseases Transmitted by Oral or Gastrointestinal Infection

November 5
Background (Text, p. 686-689), Dental Caries (Text, p. 689-691), Periodontal Disease (Text, p. 691-693), Oral Herpes (Text, p. 756, 758; Article: "Hope "), Thrush (Wikipedia), Mumps (Text, p. 693-695)
November 10
Ulcers (Text, p. 696-697; Article: "Family Size Affects the Development of Stomach Cancer"), Botulism (Text, p. 183, 200, 603-605), Staphylococcal Intoxication (Text, p. 709-710, 794-798), Mycotoxicosis (Text, p. no coverage in text), Enteritis (Text, p. 687,
November 12
Giardiasis (Text, p. 713-714), Cryptosporidiosis (Text, p. 119, 142, 706-707), Dysentery (Text, p. 699-700, 714-715), Cholera (Text, p. 702-704), Typhoid Fever (Text, p. 697-698), Hepatitis A & E (Text, p. 715-717; Article: "Doctor in hepatitis B case has license suspended")
November 17
Polio (Text, p. 592-595), Toxoplasmosis (Text, p. 592-593), Pinworm (Text, p. 719, 722-725; Article: "Battling the Worms Inside You"), Trichinosis (Text, p. 726-727), Tapeworm (Text, p. 719, 722-723), Mad Cow Disease (Text, p. 173-174, 588-590)

Diseases Transmitted by Genitourinary Infection

November 24
Background (Text, p. 736-738), Cystitis (Text, p. 739-742; Article: "Treatments for Urinary Infections Leave Bacteria Bald, Happy and Vulnerable"), Vaginosis (Text, p. 735, Toxic Shock Syndrome(Text, p. 356, 454)
December 1
Gonorrhea (Text, p. 745-748), Chlamydial Disease (Text, p. 745, 748-750; Article: "2 Million Have Chlamydia")
December 3
Syphilis (Text, p. 748-752; Article: "Sex Infections Found in Quarter of Teenage Girls")
December 8
Genital Herpes (Text, p. 755-758), Genital Warts (Text, p. 758-760; Articles: "Let's Not Talk About Sex" plus "HPV vaccine prevents genital warts in males" ), Hepatitis B, C, D (Text, p. 717-719, 746)
December 10
AIDS (Text, p. 55, 533, 636-645, 735-736, 744; Article: "Living with HIV")
Review, Synthesis and Integration of Concepts
December 17
Final Examination - 10:15-12:15 (room 112 PSN)

Reading


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Credit/No-Credit Courses

Warning: Nationwide studies have shown that credit/no-credit grades on your academic record may be a negative factor in evaluation of your application for admission or employment by most professional schools (Text, p. law, medicine, etc.), by many graduate schools, and by some employers and undergraduate schools. Before enrolling for courses on a credit/no-credit basis consider what effect it may have upon your career goals.

The following are only the most problematic of the Credit/No-Credit rules ... A full-text version can be accessed in Section 1.2.H of Chapter 2 of Part 1: Undergraduate Academic Regulations of the 2009-2010 Student Handbook ... or on the Micro FAQs web page.

Students should consult with the chief departmental adviser of their department of major with questions pertaining to courses that may be taken on a credit/no-credit basis.


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© 1995-2009 John R. Stevenson. All Rights Reserved

Please
email questions and comments to:
John R. Stevenson, Ph.D.
Associate Professor
Department of Microbiology
Miami University
Oxford, Ohio 45056
USA
This document was last modified on Wednesday, 04-Nov-2009 23:21:00 EST