111
Microorganisms and Human Disease
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Course Outline - Fall 2009
Principles of Disease, Microorganisms as Parasitic Agents, and Epidemiology
- August 25
- Introduction and
Overview
(Text, p. 1-3, 5-17)
- Infectious Disease Principles (Text, p. 6-7, 16-17, 379-405)
- August 27
- Description of Microorganisms: Bacteria (Text, p. 86-106, 192-197,
199-202) and Viruses (Text, p. 149, 166, 172-174), Eukaryotic Cells (Text, p. 117-129), Fungi (Text, p. 130-135), Protozoa
(Text, p. 136-142, 181), Helminths (Text, p. 143-145)
- September 1
- Infectious Strategies
of Microorganisms:
Virulence Factors (Text, p. 141t, 383-392; Articles: "Study
Immuminates How The Plague Bacteria Causes Disease" plus "Scientists
Reveal How H5N1 Kills")
- Epidemiology Principles (Text, p. 405-413; Article: "Salmonella
Outbreak" plus "Eat
That Tomato!" plus "Peanut
Butter Link to Salmonella Outbreak")
Impact of Infectious Diseases on Development of Human
Societies
- September 3
- Antiquity to
Middle Ages: Malaria (Text, p. 627-632), African Sleeping Sickness (Text, p. 599-601),
Schistosomiasis (Text, p. 725-726), Leprosy (Text, p. 358; Article: "Leprosy
Was Spread by Colonialism, Slave Trade"), Plague (Text, p. 314, 615-617, 677; Article: "Bubonic
Plague Traced to Ancient Egypt")
- Middle Ages to
Dawn of Microbiology as a Science: Overview (Text, p. 345),
Plague (Text, p. 314, 615-617, 677),
Smallpox (Text, p. 465, 549-551; Article:
"Smallpox
and Other Deadly Eurasian Germs")
- September 8
- Middle Ages to Dawn of Microbiology
as a Science: Overview (Text, p. 345; Article: "Guns,
Germs and Steel"),
Syphilis (Text, p. 748-752), Cholera (Text, p. 702-704; Article: "How
Epidemics Helped Shape the Modern Metropolis"),
Tuberculosis (Text, p. 343, 354)
- Era of Public
Health and Discovery of Antibiotics: Overview (Text, p. 15-16, 349), Syphilis
(Text, p. 748-752), Typhoid
Fever (Text, p. 397, 697-698), Tuberculosis
(Text, p. 666-671), Influenza (Text, p. 662-666; Video: "1918
Flu")
- September10
- Last 50
Years: AIDS (Text, p. 634-642, 733-734, 742),
Avian Flu (Video: "Pandemic
Flu") , Dengue
Fever (Text, p. 622-623), Ebola Fever (Text,
p. 623-624; Article: "Where
Does Ebola Hide between Epidemics?"), Hantavirus Respiratory
Syndrome (Text, p. 675),
Legionnaire’s
Disease (Text, p. 674), Lyme Disease (Text,
p. 618-621), Mad Cow Disease (Text, p. 173-174,
588-590), SARS (Text, p. 149, 166, 675-677),
West Nile Fever (Text, p. 585-586)
Human Defenses against Parasitism
- September 15
- Innate Host Defenses: Resistance (Text, p. 414-441)
- September 17
- Innate Host Defenses: Resistance (Text, p. 414-441)
- Adaptive Host Defenses: Immunity (Text, p. 442-477)
- September 22
- Adaptive Host Defenses: Immunity (Text, p. 442-477)
- September 24
- Coping Strategies:
Vaccines (Text,
p. 464-473; Articles: "Vexing
Vaccines" plus
"No
Link Between Measles Vaccine and Autism"), Disinfection (Text,
p. 327-337, 794-798), Antimicrobial
Chemotherapeutic Agents (CTAs) (Text, p.
246-249, 343-370)
- Review, Synthesis and Integration of Concepts
- September 29
- Examination 1
Diseases Transmitted by Skin Infection
- October 1
- Background (Text, p. 535-538), Acne (Text, p. 538;
Article:
"Understanding
Acne"), Impetigo (Text, p. 540-543), Furuncles (Text, p. 538,
544), Necrotizing
Fasciitis (Text, p. 539), Candidiasis (Text, p. 135,
353, Wikipedia)
- October 6
- Tineas (Text, p. 558-561), Sporotrichosis (Wikipedia), Warts (Text, p. 555-557), Cutaneous
Herpes (Wikipedia), Gangrene (Text, p. 545-546), Tetanus (Text, p. 596-597)
- October 8
- Anthrax (Text, p. 558, 632-633), Leprosy (Text, p. 358;
Article: "Leprosy
is not dead"), Ebola Fever (Text, p. 623-624), Rabies (Text, p. 590-592), Plague (Text, p. 615-617,
677), Lyme Disease (Text, p. 618-621), Rocky
Mountain Spotted Fever (Text, p. 626-632)
- October 13
- Encephalitis (Text, p. 585-586, 626-627), Dengue
Fever (Text, p. 622-623), Yellow
Fever (Text, p. 623), Malaria (Text, p. 627-632; Article:
"The
Story of Malaria and other Deadly Tropical Germs"), African
Sleeping Sickness (Text, p. 599-601), Schistosomiasis (Text, p. 725-726)
Diseases Transmitted by Respiratory Infection
- October 15
- Background (Text, p. 650-651), Colds (Text, p. 651-652,
661), Streptococcal Pharyngitis (Text, p. 555, 654-657), Otitis
Media (Text, p. 653-654), Meningitis (Text, p. 574-578)
- October 20
- Rubella (Text, p. 553-554), Rubeola (Text, p. 535,
551-553, 555; Articles: "MMR
doctor Andrew Wakefield fixed data on autism" plus "Most
US Measles Cases Reported since 1996"), Varicella (Text, p. 546-549)
- October 22
- Variola (Smallpox) (Text, p. 465, 549-551), Infectious
Mononucleosis (Text, p. 621-622), Diphtheria (Text, p. 657-659), Pertussis (Text, p. 649,
661)
- October 27
- Influenza (Text, p. 662-666; Articles: "Southern
Hemisphere's swine flu experience holds hints of what may be ahead" plus "Health
Expert Says Swine Flu Not Likely to Mirror 1918 Pandemic"), Pneumonia (Text, p. 671-675), Legionaire's
Disease (Text, p. 676), Hantavirus
Respiratory Syndrome (Text, p. 675)
- October 29
- Tuberculosis (Text, p. 666-671;
Article: "Drug
Resistant TB May Be Treatable"), Histoplasmosis (Text, p. 677-679)
- Review, Synthesis and Integration of Concepts
- November 3
- Examination 2
Diseases Transmitted by Oral or Gastrointestinal Infection
- November 5
- Background (Text,
p. 686-689), Dental
Caries (Text, p. 689-691), Periodontal
Disease (Text, p. 691-693), Oral Herpes (Text,
p. 756, 758; Article: "Hope
"), Thrush (Wikipedia), Mumps (Text,
p. 693-695)
- November 10
- Ulcers (Text, p. 696-697;
Article: "Family
Size Affects the Development of Stomach Cancer"), Botulism (Text, p. 183,
200, 603-605), Staphylococcal Intoxication (Text, p. 709-710,
794-798), Mycotoxicosis (Text, p. no coverage in text), Enteritis (Text, p. 687,
- November 12
- Giardiasis (Text, p. 713-714), Cryptosporidiosis (Text, p. 119,
142, 706-707), Dysentery (Text, p. 699-700,
714-715), Cholera (Text, p. 702-704), Typhoid
Fever (Text, p. 697-698), Hepatitis
A & E (Text, p. 715-717; Article: "Doctor
in hepatitis B case has license suspended")
- November 17
- Polio (Text, p. 592-595), Toxoplasmosis (Text, p. 592-593), Pinworm (Text, p. 719,
722-725; Article: "Battling
the Worms Inside You"), Trichinosis (Text, p. 726-727), Tapeworm (Text, p. 719,
722-723), Mad Cow Disease (Text, p. 173-174, 588-590)
Diseases Transmitted by Genitourinary Infection
- November 24
- Background (Text, p. 736-738), Cystitis (Text, p. 739-742;
Article: "Treatments
for Urinary Infections Leave Bacteria Bald, Happy and Vulnerable"), Vaginosis (Text, p. 735,
Toxic Shock Syndrome(Text, p. 356, 454)
- December 1
- Gonorrhea (Text, p. 745-748), Chlamydial
Disease (Text, p. 745, 748-750; Article: "2
Million Have Chlamydia")
- December 3
- Syphilis (Text, p. 748-752;
Article: "Sex
Infections Found in Quarter of Teenage Girls")
- December 8
- Genital Herpes (Text, p. 755-758), Genital
Warts (Text, p. 758-760; Articles: "Let's
Not Talk About Sex" plus "HPV
vaccine prevents genital warts in males" ), Hepatitis
B, C, D (Text, p. 717-719,
746)
- December 10
- AIDS (Text, p. 55, 533, 636-645, 735-736, 744;
Article: "Living
with HIV")
- Review, Synthesis and Integration of Concepts
- December 17
- Final Examination - 10:15-12:15 (room 112
PSN)
Reading
- Textbook - Cowan and Talaro. 2009. Microbiology:
A Systems Approach, 2nd Ed. McGraw-Hill, Dubuque, IA. (Text, p. The numbers
in parentheses following each topic
listing are the page numbers in the text to read
to gain more insight into each topic.)
- I have generated an extensive Microorganisms and
Human Disease web site that includes study
guides for you to use as supplements to the
material I present in lecture.
- The button bar
(Text, p. below) appears at the bottom of every page in the web
site, and can be used to navigate to any other page in
the site.
- The study
guides contain links to other
web sites in addition to material that I have
written ... please understand that the web site is a
dynamic entity (Text, p. e.g., it is continually being
updated and improved) and use it as such.
- I have also selected a number of
articles for you to read.
- The titles of these articles are links in
parentheses associated with the topic to which they
pertain in the Course
Outline (Text, p. above).
- If a link doesnot immediately open the article, you can find a copy in the Course
Documents section of the the MBI
111 Blackboard Website.
- You are expected to read all these
articles and be prepared to answer questions about
them on the examinations to which they
pertain.
- Some of these links will allow you to access Adobe pdf files,
but this requires Acrobat Reader:
- You can download a FREE copy of Acrobat Reader by clicking on this button:

- Follow the instructions on the Adobe web page to be sure to down load the correct version
for your computer's operating system
- Finish up by following the instructions to instal Adobe Reader on your computer
- I have also selected a number of videos for you to watch.
- The titles of these videos are links in parentheses associated with the topic
to which they pertain in the Course Outline (Text, p. above).
- You are expected to watch all these videos and be prepared to answer questions
about them on the examinations to which they pertain.
Withdrawal Policy
Credit/No-Credit Courses
Warning: Nationwide studies have shown
that credit/no-credit grades on your academic record may be a negative
factor in evaluation of your application for admission or employment
by most professional schools (Text, p. law, medicine, etc.), by many graduate
schools, and by some employers and undergraduate schools. Before
enrolling for courses on a credit/no-credit basis consider what
effect it may have upon your career goals.
The following are only the most problematic of the Credit/No-Credit
rules ... A full-text version can be accessed in Section
1.2.H of Chapter
2 of Part 1: Undergraduate Academic Regulations of
the 2009-2010 Student Handbook ...
or on the Micro
FAQs web page.
- 01.208.E. “Credit” (Text, p. X) will be granted
for grades C through A; “no-credit” (Text, p. Y) will be
granted for grades C- or less.
- 01.208.H. Course status may not be changed
from credit/no-credit to letter grade nor from letter grade to
credit/no-credit after 20 percent of the class meeting times have
elapsed.
- 01.208.I. Registration in a course on a credit/no-credit
basis requires the permission of the instructor except in
Miami Plan or University Requirement courses.
Students should consult with the chief departmental adviser
of their department of major with questions pertaining to courses
that may be taken on a credit/no-credit basis.
© 1995-2009 John R. Stevenson. All
Rights Reserved
Please email
questions and comments to:
John
R. Stevenson, Ph.D.
Associate Professor
Department of Microbiology
Miami University
Oxford, Ohio 45056
USA
This document was last modified on Wednesday, 04-Nov-2009 23:21:00 EST