<%@LANGUAGE="JAVASCRIPT" CODEPAGE="1252"%> Syllabus

Genetic 342 A&B

Kenneth G Wilson

Professory of Botany

 

Instructor Ken Wilson Linda Hartman
Office hours

Tuesday 11:00 - 1:00, 3:30-500

Thursday 11:00- 12:00

Or by appointment

Mon 12-2pm

or by appointment

Email wilsonkg@muohio.edu hartmals@muohio.edu
Office 367C Pearson 353G Pearson

 

Date Topic Detail Chapter
9 Jan Scientific Method

General Scientific Method
Occams Razor
The Phases of Science
Paradigm Shift - Thomas S. Kuhn

 

Informational Macromolecules

History

Johann Friedrich Miescher

Frederick Griffith

Erwin Chargaff - (A+T)/(G+C);A=T;G=C

 

10
11 Jan Is DNA Genetic Material?

Transformation : Fredrich Griffith
, Avery, McCarty, McLeod

Phage Homogenization:
Alfred Hershey & Martha Chase

Reconstitution: Heinz Fraenkel-Conrat and Bea Singer's TMV

10
16 Jan Data used to build the Model

DNA Structure before Watson & Crick 1953

 
The Model The Double Helix
Predictions from the Model Semiconservative Replication
A pair with T and C with G
Proof of the Double Helix Model Meselson and Stahl
Kornberg's Nearest Neighbor (Will cover after Replcation)
12
Properties of DNA    
18 Jan Chromosome

Eukaryotic
Bacterial
Organellar
Virus

11
23 Jan Replication

Double Helix
Bi-directional
Leading Lagging
Polymerase


12
25 Jan Catch up New from Utube - DNA Replication  
30 Jan catch up
 
01 Feb Exam Study Sheet  
06 Feb Heredity Pre Mendel
Mendel

1
3

08 Feb   Beyond 3, 15
13 Feb   Dihybrids 3
15 Feb Sex

Interactions genes and sex
Determination of Sex

4
20 Feb No Class (M/T)    
22 Feb Genes & Chromosomes

linkage
Sturtevant

 

chap 7
27 Feb  

Predictions

3 point linkage

Sex Linkage

chap 4
01 Mar Cell Division

Three point prediction
cis-trans test
Fission
Mitosis
Meiosis flash

cell cycle flash

chap 2
06 Mar  

Summation of C/O
Proof of C/O

 
08 Mar  

Holliday Junction

Non-linked modifications

chap 5
13-15 Mar Spring Break Study Sheet II  
20 Mar Open Study Session: 112 PSN 5-7 pm

Central Dogma
Code Cracking
Transcription

chap13
22 Mar Exam Section    
27 Mar

Term Project

web sites

   
29 Mar      
03 Apr family fun What is a gene/cistron  
05 Apr Eukaryotic mRNA

Capping and capped

Tailing

Processing (animation)

 

14
10 Apr  

Introns

Editing

Si and Mi RNA

 
12 Apr  

Lactose

Lactose Regulation


Engineering tools
sequencing
Mouse globin genes - TATA box
Reverse Genetics - Start with protein and work backwards - This is really the genetics of the future.

 

 
17 Apr My Last Lecture
order Genetics Reverse Genetics
1 Mutant Phenotype Protein Sequence
2 Mutant Allele DNA Sequence
3 DNA Sequence Mutant Allele - Knock Out Technology
4 Protein Sequence Mutant Phenotype

 

Oliver

 
19 Apr Exam Study Sheet 3  
24 Apr Guest Lecture Chun Liang  
26 Apr Presentations

Section A

Section B

A- Pan troglodytes
B - Gallus gallus
F - Xenopus tropicalis
G - Homo sapiens
BB - Takifugu rubripes
FF - Plasmodium falciparum/Anopheles gambia

GG - Arabidopsis thaliana
HH - Gallus gallus
01 May

Final -

Section B

12:30

Presentations
AA - Pan troglodytes
CC - Drosophilia melanogaster
DD - Xenopus tropicalis
EE - Mus musculus
II - Caenorhabditus elegans

 
04 May

Final -

Section A
2:45 pm

Presentations
C - Mus musculus
D - Plasmodium falciparum
E - Drosophilia melanogaster
H - Schmidtea mediterranea

 

 

Old Notes: 2005

 

text/pics

oliver

This is our friend Oliver the parrotlet,

Oliver is a true parrot,

the smallest in the world.